Efficacy of certain agents in controlling immunosuppressive effects of Infectious Bursal Disease virus in chicken

Manoj Kumar and K.C.P.Singh
Department of Veterinary Microbiology
Bihar Veterinary College , Patna – 800 014

An attempt was made of enhance the immune response and production potential with certain agents i.e. Levamisole hydrochloride (7.5 mg/kg body wt.), Polyzyme (PZ, 0.05%), dl-α-tocopherol acetate (VE, 125 mg/bird), Emblica officialis fruit EO, 80 mg/ bird), Cannabis sativa leaves (CS, 40 mg/bird) and Carbo animalis (CA, 20 ml/litre of water) in broiler diets. A reference diet was devoid of any treatment and served as the control. All the birds were provided standard ration. Three hundred and fifty broiler were divided into seven equal groups and housed in intensive deep litter system and identical management conditions were maintained for all birds. Each diet was offered ad-libitum from 5 to 45 day of age to 50 birds in each group. All the birds were vaccinated against Ranikhet disease (RD) by F and LaSota strain on 5 and 25 day of age. Vaccination was also done against infectious bursal disease (IBD) by IV 95 strain. Blood samples from five representative birds of each group were collected for sera on 17, 24, 31, 38, 45 day of age. Haemagglutination inhibition (HI) and Quantitative agar gel precipitation test (QAGPT) was conducted assess the immune response against RD and IBD, respectively. Body weight gain and feed conversion ratio were determined for each group.

The HI antibody titre was highest for CS treated group followed by EO, VE , CA , PZ treated and control group. The QAGPT titre was highest for CS treated group followed by EO, CA, VE, LH, PZ and control group. The body weight gain and was highest for CS treated group followed by EO, VE, LH, CA, PZ and control group, whereas the FCR value was highest in CS treated group followed by control, EO, VE, PZ, CA, LH group. It is concluded that two herbal products used in the present study was most effective in improving the immunity and production potential of the chicken, however, overall performance in other treatment groups were betters compared to control group. The role of feed supplement will be discussed in detail.

Source : IPSACON-2005

Did You Like This Article? Bookmark it at Del.icio.us

Article Tools