Effect of dietary fenvelerate on clinical signs, gross histopathological lesions in broilers

R.K. Misra, A.K. Misra and P.K. Shukla
Department of Poultry Science College of Veterinary Science & A.H.
Mathura – 281 001 (U.P.)

An investigation was carried out to study the toxicological effect of Fenvelerate (75 or 100 ppm) in commercial broilers from 2 nd to 7 th weeks of age. At 7 weeks of age two birds from each replicate group were slaughtered to conduct the PM and subsequent histopathological studies of various visceral organs. In the present experiment the clinical symptoms in the birds fed FEN (100 ppm) appeared in the last week of trial, which were characterized by dullness and occasional diarrhea. The birds maintained on FEN 75 ppm appeared to be healthy and normal without noticing any appreciable clinical symptoms. The gross pathological lesions in broilers were observed as slight enlargement and hemorrhages at the periphery in the liver of the birds fed FEN 100 ppm. Spleen showed enlargement, congestion and was covered with pinpoint hemorrhages. There was a little atrophy of bursa. Kidney showed mild congestion, whereas heart revealed pinpoint hemorrhages & slight hydropericarditis.

Histopathological examination of liver of the birds fed FEN 100 ppm depicted engorged hepatic blood vessels; degenerative changes in the hepatic cells and the hepatocytes were swollen showing lymphoid aggregation. Bursa showed engorged blood vessels with marked degeneration. No appreciable pathological changes have been observed in the spleen except mild depletion of lymphoid cells. The heart showed mild degenerative changes in the myocardium and the lungs showed congestion, hemorrhages and the presence of serofirinous exudates around the blood vessels.

Source : IPSACON-2005

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