Isolation and characterization of Paramyxovirus type - 1(PPMV-1) from pigeons

K.A. Naveen, S.D. Singh, T.R. Mohanty and J.M. Kataria
Division of Avian Diseases, I.V.R.I. Izatnagar, U.P. 243 122

Newcastle disease virus (NDV) causes a fetal disease in pigeons and primarily associated with neurological signs. The NDV isolates obtained from diseased pigeons are termed Pigeon Paramyxovirus-1 (PPMV-1). This paper describes the isolation of a PPMV-1 from pigeons showing clinical signs of diarrhea, tremor, ataxia torticolis and paralysis of wings. The mean death time (MDT), intra-cerebral pathogenicity index (ICPI) and intravenous pathogenicity index (IVPI) of the isolate was 112 h, 0.42 and 0.0 respectively, suggesting it to be lentogenic. However pigeons experimentally inoculated with the isolate became sick and died. The amino acid sequence at the F 2/F 1 cleavage site was 112 RRQKRF 117, which is typical of virulent NDV. These results provide further evidence about the pathotyping problems of PPMV-1.

Source : IPSACON-2005

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