Comparative antioxidant efficacy of herbal E-50 and synthetic vitamin E
S. CHATTERJEE AND S.K.AGRAWALA
Indian Herbs Research & Supply Co Ltd
Vitamin E is an essential nutrient to help prevent oxidative damage to biomembranes, improve immune functions and to optimize fertility and hatchability in breeders besides improving production performance in poultry birds. Vitamin E is a known lipid phase antioxidant and also stabilizes cell membrane. Herbal E-50 is a unique product that contains vitamin E in natural and highly bioavailable form, which gets quickly absorbed, slowly excreted and is more active as compared to synthetic Vitamin E. The antioxidant activity of Herbal E-50 was determined and compared with synthetic Vitamin E (DL- a-tocopherol). The efficacy was tested in lipid phase of biological system and the oxidative stress was induced by appropriate media (Fe-ascorbate). The generated oxygen radicals were scavenged by Vitamin E and/or Herbal E. The efficacy of both the products was calculated in terms of IC50 (the concentration of product required to inhibit 50% of generated free radicals in the system). It was observed that the antioxidant activity of Herbal E-50 is nearly three times more (IC50: 0.029 mM/ml) as compared to synthetic Vitamin E (IC50: 0.071 mM/ml). The present study clearly indicates that Herbal E-50 is significantly more potent as compared to synthetic Vitamin E and will exert better physiological response at same concentration level.